a group of Indian researchers has developed a technique that will use a commonly-found freshwater fish as a model for testing drugs for type ii diabetes. Popular methods till now have relied on mammals for the study, but their use presents economic, legal and practical difficulties.
Conducted by scientists from the Indian Institute of Chemical Biology, Kolkata and School of Life Science, Visva Bharti, the study found that the Indian perch (Anabas testudineus) treated with palmitic acid, a type of fatty acid, can develop insulin resistance -- a condition similar to type ii diabetes in mammals. This condition can be used conveniently as a model for testing potential therapeutic compounds, as per the study published in Current Science (Vol 90,No 2, January 25,2006).
The scientists say the fish is easy to maintain and breed in the lab.
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