Slim chances

Last Updated: Saturday 04 July 2015

HERE is good news for all those trying to beat hunger pangs and stay on the slimmer side. Scientists from the institute of Health and Medical Sciences (INSERM), France, are a few steps away from developing a new diet control therapy that involves the use of neurotransmitters, which are chemicals that brain cells use to communicate with each other. Researchers have been studying an a ppetite- related neurotransmitter called CCK-8, that is usually produced after food intake to control the appetite of the eater. This neurotransmitter signals the eater through the brain cells to stop eating.

Now scientists are trying to use CCK-8, also known as 'satiety molecule', as a possible appetite-suppression agent for people who should be on diet but just cannot cut down their appetite for delicious food. Researchers at INSERM identified an enzyme TPP11, which breaks, down CCK-8 in the digestive tract before it can regulate diet. They have also designed a chemical, butabindide, which would inactivate TPPII and enable CCK-8 to do its appetite-suppressing job.

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