According to previous research, blood clotting is a major cause of death in COVID-19 patients
Irish scientists have found out how and why novel coronavirus disease (COVID-19) patients develop blood clots. The study was done by Researchers from Royal College of Surgeons in Ireland University of Medicine and Health Sciences.
The study found that the balance between the von Willebrand Factor (VWF) and ADAMTS13 is severely disrupted in patients with severe COVID-19 infection. VMF is a protein that causes blood clots and ADAMTS13 is an enzyme that regulates clotting.
The researchers took and examined blood samples from patients with COVID-19 in the Beaumont Hospital Intensive Care Unit in Dublin. The researchers then compared the blood of COVID-19 patients with non-COVID patients.
The blood of COVID-19 patients had higher levels of the pro-clotting VWF molecules and lower levels of the anti-clotting ADAMTS13. The researchers also identified other changes in the proteins that caused a drop in ADAMTS13. According to previous research, blood clotting is a major cause of death in COVID-19 patients.
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